Why is sickle cell disease a recessive trait

For these, please consult a doctor virtually or in person. For potential or actual medical emergencies, immediately call or your local emergency service. Ask your question Ask question Free. HealthTap doctors are based in the U. Video chat with a U.

Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. Connect with a doctor now. Get help now: Ask doctors free Educational text. What it the probability that a couple's child will be afflicted with sickle cell anemia if they both carry that trait but don't exhibit it?

A Verified Doctor answered. A US doctor answered Learn more. I have sickle cell anemia trait can that affect me? John Munshower answered. Family Medicine 30 years experience. Usually not: Sickle cell trait is a hemoglobin genotype as and is generally regarded as a benign condition.

However, individuals with sickle cell trait may have ra If a child has sickle cell anemia, wouldn't both the parents need to have sickle cell trait?

Robin Larabee answered. The severity of symptoms is also used to help determine what is the proper treatment. If the right drug s are not given in the correct dosages for the correct amount of time, symptoms may return.

This is more common in the species P. Prevention There are no vaccines for malaria, so only precautionary actions can be taken to prevent malaria infection.

Often, drugs used in treatment will be prescribed as a preventative drug for people traveling to places where malaria is common. Other effective prevention efforts include sleeping under mosquito nets, spraying insecticide on the walls in the home, covering skin with clothing, and using insect repellants.

The microRNAs are transformed into the parasite and are inserted into its mRNA in a method similar to trans-splicing or splice-leader trans-splicing, inhibiting translation and reducing P. Sickle Cell Trait Protects Against Plasmodium falciparum Infection "Sickle Cell Trait Protects Against Plasmodium falciparum Infection" addresses whether sickle cell trait is effective in protecting carrier children from asymptomatic malaria caused by P. If the carrier is protected from asymptomatic malaria, then sickle cell trait is doing more than decreasing the severity of symptoms and is actually affecting the parasite.

The study was carried out in a village in Mali over two years and included children— of whom were positive for P. Children with HbAS had lower concentration of P.

Additionally, children initially negative for P. The results of this study indicate sickle cell trait does protect the carrier from asymptomatic malaria as well as symptomatic malaria. It is widely accepted that sickle cell trait protects the carrier from malaria both symptomatic and asymptomatic , yet all of the mechanisms are still not fully understood.

People with SCT who participate in competitive or team sports i. To prevent illness it is important to:. Skip directly to site content Skip directly to page options Skip directly to A-Z link. Section Navigation. Facebook Twitter LinkedIn Syndicate. As illustrated, the couple has one chance in four that the child will have the genes both for sickle hemoglobin and for thalassemia.

The child would have sickle b -thalassemia. The severity of this condition is quite variable.